Pepti Smile Toothpaste
$15.00
Pepti Smile Toothpaste is a peptide-enriched oral care formulation that delivers three bioactive peptides — BPC-157, KPV, and Palmitoyl Tetrapeptide-7 — within a functional toothpaste matrix designed for daily use.
This formulation bridges advanced peptide science with practical oral hygiene, offering clinicians and patients a product where mucosal support, anti-inflammatory activity, and tissue conditioning are built directly into the brushing experience. The ingredient architecture maintains peptide stability and bioavailability alongside proven oral care compounds.
- Advanced Peptide Complex featuring BPC-157 (tissue-protective), KPV (anti-inflammatory), and Palmitoyl Tetrapeptide-7 (cytokine modulation)
- Professional-grade oral care base with Calcium Carbonate, Hydrated Silica, Xylitol, and humectant systems
- Formulated to support mucosal health, tissue recovery, and inflammatory balance within a daily hygiene protocol
In stock

Volume Discounts
Bulk Volume Discounts starting as low as 20 units per Product

Custom Labeling
3 Tiers of labeling: Unlabeled, Generic, and Custom Label

Quality Guarantee
All products come with a 30-Day Quality Guarantee.

US-Based Support
US-based support available Monday - Friday 7-6pm ET
Description
PeptiSmile™ Advanced Peptide Toothpaste
Oral care has finally caught up with the rest of your routine
You’ve upgraded your skincare. You read ingredient labels. You know the difference between a formula built on actives and one built on filler. So why is your toothpaste still stuck in 1995?
Most toothpaste does one job — scrub the surface of your teeth and leave behind a mint flavor. But your mouth is more than enamel. Your gums and soft tissue take a beating every single day from brushing, acidic food, coffee, and bacteria. PeptiSmile™ was built around that reality.
It pairs a multi-peptide complex — the same class of ingredients that drive the most advanced skincare on the market — with clean, purpose-selected oral-care ingredients. The result is a toothpaste that still delivers the fresh, polished-clean feeling you expect, while treating your whole mouth like the living tissue it is.
The Peptide Complex
Peptides are short chains of amino acids — the same building blocks your body uses to signal, repair, and maintain tissue. They’re the reason peptide serums command premium prices in skincare. PeptiSmile™ brings three of them into a daily oral-care format.
BPC-157
A synthetic peptide modeled on a sequence found naturally in gastric juice — its name stands for “Body Protection Compound.” In research settings, BPC-157 is studied for its role in tissue support and the body’s natural repair signaling, which is exactly why it’s developed a following in the recovery and wellness world. In PeptiSmile™, it’s the lead peptide in a complex built around the gumline.
KPV
A tripeptide (lysine-proline-valine) that’s the active tail-end fragment of alpha-MSH, one of your body’s own signaling molecules. KPV is studied specifically for its calming, anti-inflammatory signaling at the cellular level — relevant anywhere tissue is under constant daily stress, and the gumline qualifies.
Palmitoyl Tetrapeptide-7
If you’ve used a high-end anti-aging serum, you’ve likely already used this one. It’s a signaling peptide prized in advanced skincare for supporting the structure and resilience of soft tissue. PeptiSmile™ brings that same skincare-grade ingredient into your oral-care routine, where it rounds out the peptide complex.
The Supporting Cast
Great actives need a great base. Every other ingredient in PeptiSmile™ earns its place.
Tranexamic Acid
Not a trend — a professional staple. Dentists and oral surgeons have relied on tranexamic acid for decades to support gums prone to bleeding, and dermatologists love it for tone and clarity. Having it in your daily tube means that level of support is built into your routine, not something you only get in a clinic.
Xylitol
A naturally derived sweetener with a useful trick: the bacteria responsible for tooth decay can’t ferment it, so it doesn’t feed the cycle that causes cavities. It’s been a fixture in serious oral care and dental gum for years — and it makes the paste taste clean without sugar.
Vitamin E (Tocopherol)
A well-known antioxidant that keeps the formula stable and is gentle on the soft tissue of the mouth.
Dipotassium Glycyrrhizinate
Derived from licorice root, this soothing, mildly sweet ingredient is a go-to for cosmetic formulators in products designed for sensitive areas. It helps keep the overall formula gentle.
What Makes PeptiSmile™ Different
| Standard Toothpaste | PeptiSmile™ |
| Cleans the surface of your teeth | Supports your whole mouth — teeth and soft tissue |
| One basic action, then mint | Multi-peptide complex + purpose-built actives |
| Generic, mass-market formula | Skincare-grade ingredients, precision-formulated |
| Made by the millions | Small-batch, made in the USA. |
Who It’s For
- People who already obsess over their skincare ingredients and want their oral care to match
- Anyone who’s been told to “keep an eye on the gums” and wants daily support, not just a cleaning
- Wellness enthusiasts who refuse to let one product in their routine lag behind the rest
- Anyone tired of toothpaste that promises a healthier mouth and delivers nothing but flavor
Clean Formula. No Compromises.
Built with: Triple-peptide complex · Tranexamic Acid · Xylitol · Vitamin E · Dipotassium Glycyrrhizinate
Formulated without: Parabens · Harsh sulfates · Unnecessary fillers
Every batch is made in the USA under strict quality standards, with consistency you can count on, tube after tube.
How to Use
Apply a small amount to a soft-bristle brush. Brush thoroughly for two minutes, paying extra attention along the gumline. For best results, let the formula sit for about 30 seconds before rinsing, so the peptides have time to make contact. Use twice daily alongside regular flossing and routine dental checkups.
PeptiSmile™ Advanced Peptide Toothpaste 100ml / 3.4 fl oz Modern peptide science for people who expect more from everyday products.
Professional Use Only - Legal Disclaimer
All PeptiMed products are classified as Professional Use Only (PUO) and are intended exclusively for qualified professionals, licensed facilities, and authorized organizations. These products are not approved by the FDA and are not intended for personal use, consumer use, or unsupervised application.
By purchasing or using PeptiMed products, you confirm that you are a properly licensed professional acting within the scope of your credentials and that you understand all regulatory, safety, and compliance obligations associated with handling these materials. Products must not be sold, supplied, or provided directly to consumers or used outside an appropriate professional environment.
All handling, storage, and use of PeptiMed products are undertaken at your own risk. PeptiMed assumes no responsibility for misuse, improper application, or any clinical, regulatory, or professional consequences resulting from their use.
Labeling Options
All labeled vials include product details and batch information including a QR Code* to the COA printed on each label
Labeling Options
All labeled vials include product details and batch information including a QR Code* to the COA printed on each label
No Label
PeptiMed Label
Custom Label
Private Label
*QR Codes coming in early 2026

